BDBM50592375 CHEMBL5185310

SMILES Cc1[nH]c2ccccc2c1C1=CCC(CC1)NCc1ccc(OCC(=O)NO)cc1F

InChI Key InChIKey=JWLYQKTWAMWCIV-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50592375   

TargetHistone deacetylase 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50592375(CHEMBL5185310)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50592375(CHEMBL5185310)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50592375(CHEMBL5185310)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50592375(CHEMBL5185310)
Affinity DataIC50: 13nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50592375(CHEMBL5185310)
Affinity DataIC50: 86nMAssay Description:Inhibition of HDAC8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed