BDBM50592967 CHEMBL5193593

SMILES CN(C)CN1CCC(CC1)n1c(C)nc2cnc3ccc(cc3c12)-c1cc(Cl)c(O)c(Cl)c1

InChI Key InChIKey=UMHUIFOWXDUSGE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50592967   

TargetTyrosine-protein kinase JAK1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50592967(CHEMBL5193593)
Affinity DataIC50: 7.40nMAssay Description:Inhibition of JAK1 (unknown origin) using Kinase/Tyr 6 peptide as substrate incubated for 1 hrs in presence of ATP by fluorescence microplate reader ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50592967(CHEMBL5193593)
Affinity DataIC50: 62nMAssay Description:Inhibition of JAK3 (unknown origin) using Kinase/Tyr 6 peptide as substrate incubated for 1 hrs in presence of ATP by fluorescence microplate reader ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed