BDBM50593082 CHEMBL5182477

SMILES CN1CCN(Cc2ccc(NC(=O)CCc3cccc(c3)-c3cnc4[nH]ccc4c3)cc2C(F)(F)F)CC1

InChI Key InChIKey=OTHZCKVCMMTCRJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50593082   

TargetCyclin-dependent kinase 8(Human)
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50593082(CHEMBL5182477)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of CDK8 in human HCT-116 cells transfected with TOPFlash luciferase reporter plasmid assessed as reduction in TCF/LEF transcriptional acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed