BDBM50593145 CHEMBL5192784

SMILES CCCCCCN1CCN(CCC(=O)Nc2nc3c(C)cccc3s2)CC1

InChI Key InChIKey=OMCHHLIXQNKLTG-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50593145   

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Yeditepe University

Curated by ChEMBL
LigandPNGBDBM50593145(CHEMBL5192784)
Affinity DataKi:  115nMAssay Description:Displacement of [3H]ifenprodil from recombinant human GluN2B NMDA receptor (unknown origin) expressed in dexamethasone-induced mouse L-M(TK-) cell af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetSigma intracellular receptor 2(Rat)
Yeditepe University

Curated by ChEMBL
LigandPNGBDBM50593145(CHEMBL5192784)
Affinity DataKi:  158nMAssay Description:Displacement of [3H]DTG from sigma 2 receptor in rat liver membranes measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Yeditepe University

Curated by ChEMBL
LigandPNGBDBM50593145(CHEMBL5192784)
Affinity DataKi:  238nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane measured after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetCholinesterase(Human)
Yeditepe University

Curated by ChEMBL
LigandPNGBDBM50593145(CHEMBL5192784)
Affinity DataIC50: 2.93E+4nMAssay Description:Inhibition of human recombinant BuChe using butyrylthiocholine iodide as substrate incubated for 10 mins by DTNB reagent based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Yeditepe University

Curated by ChEMBL
LigandPNGBDBM50593145(CHEMBL5192784)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human recombinant AChe using acetylthiocholine iodide as substrate incubated for 10 mins by DTNB reagent based Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed