BDBM50593176 CHEMBL5174636

SMILES CC1(CCN(CC1)c1cnc(c(N)n1)-c1cccc(Cl)c1Cl)NCc1ccc(\C=C\C(=O)NO)cc1

InChI Key InChIKey=UYHZBRZIVCBSMC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50593176   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50593176(CHEMBL5174636)
Affinity DataIC50: 17nMAssay Description:Inhibition of wild type SHP2 (unknown origin) using DiFMUP as substrate preincubated for 30 mins followed by substrate addition and measured after 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHistone deacetylase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50593176(CHEMBL5174636)
Affinity DataIC50: 284nMAssay Description:Inhibition of recombinant human HDAC using fluorogenic substrate preincubated for 5 mins followed by substrate addition and measured after 30 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed