BDBM50593178 CHEMBL5203477

SMILES CC1(CCN(CC1)c1cnc(c(N)n1)-c1cccc(Cl)c1Cl)NCc1ccc(cc1)C(=O)NO

InChI Key InChIKey=IRWBTWYNFIGFIC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50593178   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50593178(CHEMBL5203477)
Affinity DataIC50: 23nMAssay Description:Inhibition of wild type SHP2 (unknown origin) using DiFMUP as substrate preincubated for 30 mins followed by substrate addition and measured after 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHistone deacetylase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50593178(CHEMBL5203477)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human HDAC using fluorogenic substrate preincubated for 5 mins followed by substrate addition and measured after 30 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed