BDBM50593209 CHEMBL5198433

SMILES O=C(Nc1nccs1)C(N1Cc2ccc(cc2C1=O)C#Cc1ccc(CN2CCCCC2)cc1)c1ncn2CCCc12

InChI Key InChIKey=GVOVNRNBMZTWHO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50593209   

TargetEpidermal growth factor receptor(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50593209(CHEMBL5198433)
Affinity DataIC50: 16nMAssay Description:Inhibition of EGFR L858R/T790M/C797S mutant (unknown origin) phosphorylation expressed in mouse BaF3 cells measured after 4 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50593209(CHEMBL5198433)
Affinity DataIC50: 342nMAssay Description:Inhibition of EGFR L858R/C797S mutant (unknown origin) phosphorylation expressed in mouse BaF3 cells measured after 4 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed