BDBM50593210 CHEMBL5172668

SMILES Fc1cc(cc2C(=O)N(Cc12)C(C(=O)Nc1nccs1)c1ncn2CCCc12)C#Cc1ccc(CN2CCCCC2)cc1

InChI Key InChIKey=HTJDDZPMJOPDOY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50593210   

TargetEpidermal growth factor receptor(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50593210(CHEMBL5172668)
Affinity DataIC50: 7nMAssay Description:Inhibition of EGFR L858R/T790M/C797S mutant (unknown origin) phosphorylation expressed in mouse BaF3 cells measured after 4 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50593210(CHEMBL5172668)
Affinity DataIC50: 54nMAssay Description:Inhibition of EGFR L858R/C797S mutant (unknown origin) phosphorylation expressed in mouse BaF3 cells measured after 4 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed