BDBM50593278 CHEMBL5180377

SMILES COC(=O)Nc1ccc2-c3nc([nH]c3C(=O)OC)[C@H](CCCC(C)(C)C(=O)Nc2c1)c1ccc(c[n+]1[O-])-c1cc(F)ccc1-n1cc(cn1)C(F)(F)F

InChI Key InChIKey=OFHANMCEQQHHAZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50593278   

TargetCoagulation factor XI(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50593278(CHEMBL5180377)
Affinity DataIC50: 0.810nMAssay Description:Inhibition of human coagulation factor XIa using GPR-AFC as substrate preincubated for 30 mins followed by substrate addition and measured after 60 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed