BDBM50593474 CHEMBL5203282

SMILES Cc1cc(ccc1OCCN1Cc2ncccc2C=C1)C(=O)C1=C(COc2cc(O)ccc12)c1ccc(O)cc1

InChI Key InChIKey=IWMRBSFBFQITCE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50593474   

TargetEstrogen receptor(Human)
University of Kragujevac

Curated by ChEMBL
LigandPNGBDBM50593474(CHEMBL5203282)
Affinity DataIC50: 1.10nMAssay Description:Antagonist activity at ERalpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetEstrogen receptor beta(Human)
University of Kragujevac

Curated by ChEMBL
LigandPNGBDBM50593474(CHEMBL5203282)
Affinity DataIC50: 70nMAssay Description:Antagonist activity at ERbeta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetProgesterone receptor(Human)
University of Kragujevac

Curated by ChEMBL
LigandPNGBDBM50593474(CHEMBL5203282)
Affinity DataIC50: 100nMAssay Description:Antagonist activity at progesterone receptor in human MCF7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetEstrogen receptor(Human)
University of Kragujevac

Curated by ChEMBL
LigandPNGBDBM50593474(CHEMBL5203282)
Affinity DataIC50: 100nMAssay Description:Antagonist activity at ERalpha in human MCF7 cells assessed as downregulation of ERalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed