BDBM50593498 CHEMBL5198066

SMILES NC(=O)C(CCC(F)(F)F)C(Cc1ccc(cc1F)-c1ncon1)S(=O)(=O)c1ccc(Cl)cc1

InChI Key InChIKey=XEMKXTDDWVUJQX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50593498   

TargetPresenilin-1(Human)
Indian Institute of Technology (B.H.U.)

Curated by ChEMBL
LigandPNGBDBM50593498(CHEMBL5198066)
Affinity DataIC50: 0.225nMAssay Description:Inhibition of gamma-secretase (unknown origin) assessed as decrease in Abeta42 levelsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed