BDBM50593522 CHEMBL5170802

SMILES COc1cc(OC)c(F)c(COc2cnc(Nc3ccc(N4CCC(CC4)N4CCN(C)CC4)c(OC)c3)nc2)c1F

InChI Key InChIKey=SYBLMCUTGSQYDI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50593522   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50593522(CHEMBL5170802)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of hERG channel expressed in CHO cells at -80 mV holding potential by Qpatch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetFibroblast growth factor receptor 3(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50593522(CHEMBL5170802)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of wild type N-terminal GST tagged FGFR3 (436 to 806 residues) (unknown origin) expressed in sf21 insect cells preincubated for 30 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed