BDBM50593555 CHEMBL5169969

SMILES C[C@@](O)(CNC(=O)c1nc(cnc1N)-c1ccc(CN2CCOCC2)cc1)C(F)(F)F

InChI Key InChIKey=VRLXXVCKJUSENY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50593555   

TargetActivin receptor type-1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50593555(CHEMBL5169969)
Affinity DataIC50: 90nMAssay Description:Inhibition of ALK2 R206H mutant (unknown origin) assessed as enzymatic activity by microfluidic mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetActivin receptor type-1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50593555(CHEMBL5169969)
Affinity DataIC50: 520nMAssay Description:Inhibition of ALK2 R206H mutant (unknown origin) transfected in BMP6-stimulated human HEK293 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed