BDBM50593680 CHEMBL5185731

SMILES COc1cccc(c1)C(=O)c1ccc2ccc(ccc12)C(O)=O

InChI Key InChIKey=MXDZTPJJLZSDRV-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50593680   

TargetCytochrome P450 2C8(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50593680(CHEMBL5185731)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of CYP2C8 in human liver microsomes using amodiaquine as substrate preincubated with compound followed by NADPH addition by LC-MS/MS analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCytochrome P450 2D6(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50593680(CHEMBL5185731)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate preincubated with compound followed by NADPH addition by LC-MS/MS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCytochrome P450 3A4(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50593680(CHEMBL5185731)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate preincubated with compound followed by NADPH addition by LC-MS/MS analysi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCytochrome P450 2C19(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50593680(CHEMBL5185731)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomes using mephenytoin as substrate preincubated with compound followed by NADPH addition by LC-MS/MS anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCytochrome P450 2C9(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50593680(CHEMBL5185731)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using diclofenac as substrate preincubated with compound followed by NADPH addition by LC-MS/MS analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed