BDBM50594014 CHEMBL5182027

SMILES OC(=O)c1cc(ccc1O)-c1ccc(CNc2ccc(Br)cc2)o1

InChI Key InChIKey=HFRKFVKJBYMRCR-UHFFFAOYSA-N

Data  2 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50594014   

Target2-Hydroxyacid oxidase 1(Human)
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM50594014(CHEMBL5182027)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of N-terminal His-tagged human recombinant glycolate oxidase expressed in Escherichia coli BL21 (DE3) cells using glycolate as substrate p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
Target2-Hydroxyacid oxidase 1(Mouse)
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM50594014(CHEMBL5182027)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of N-terminal His-tagged mouse recombinant glycolate oxidase expressed in Escherichia coli BL21 (DE3) cells using glycolate as substrate p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetL-lactate dehydrogenase A chain(Human)
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM50594014(CHEMBL5182027)
Affinity DataIC50: 600nMAssay Description:Inhibition of human recombinant LDHA using pyruvate as substrate preincubated for 10 mins followed by substrate addition and measured every 60 sec fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetL-lactate dehydrogenase B chain(Human)
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM50594014(CHEMBL5182027)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human recombinant LDHB using pyruvate as substrate preincubated for 10 mins followed by substrate addition and measured every 60 sec fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM50594014(CHEMBL5182027)
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of human COX-2 using arachidonic acid as substrate measured every 60 sec for 10 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetL-lactate dehydrogenase A chain(Human)
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM50594014(CHEMBL5182027)
Affinity DataKi:  900nMAssay Description:Non-competitive inhibition of human recombinant LDHA assessed as inhibition constant using varying concentration of pyruvate as substrate preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
Target2-Hydroxyacid oxidase 1(Human)
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM50594014(CHEMBL5182027)
Affinity DataKi:  1.10E+3nMAssay Description:Non-competitive mixed inhibition of N-terminal His-tagged human recombinant glycolate oxidase expressed in Escherichia coli BL21 (DE3) cells assessed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed