BDBM50594025 CHEMBL5179949

SMILES Fc1ccccc1NC(=O)c1ccc(NC(=O)N2CCN(CC2)C(=O)c2cc(Cc3n[nH]c(=O)c4ccccc34)ccc2F)cc1

InChI Key InChIKey=PVRVKAMGYYHFJO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50594025   

TargetPoly [ADP-ribose] polymerase 1(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50594025(CHEMBL5179949)
Affinity DataIC50: 0.980nMAssay Description:Inhibition of PARP-1 (unknown origin) using biotinylated NAD+ as substrate incubated for 45 mins in the presence of deoxy-oligonucleotide by micropla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50594025(CHEMBL5179949)
Affinity DataIC50: 296nMAssay Description:Inhibition of TNKS2 (unknown origin) using biotin-NAD+ as substrate incubated for 1 hr in the presence of deoxy-oligonucleotide by ELISA analysis rel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50594025(CHEMBL5179949)
Affinity DataIC50: 507nMAssay Description:Inhibition of TNKS1 (unknown origin) using biotin-NAD+ as substrate incubated for 1 hr in the presence of deoxy-oligonucleotide by ELISA analysis rel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed