BDBM50594027 CHEMBL5174447

SMILES Fc1ccc(Cc2n[nH]c(=O)c3ccccc23)cc1C(=O)N1CCN(CC1)C(=O)Nc1ccc(cc1)C(=O)Nc1ccc(cc1)C(F)(F)F

InChI Key InChIKey=UAVGSHVHWKPCPP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50594027   

TargetPoly [ADP-ribose] polymerase 1(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50594027(CHEMBL5174447)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of PARP-1 (unknown origin) using biotinylated NAD+ as substrate incubated for 45 mins in the presence of deoxy-oligonucleotide by micropla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50594027(CHEMBL5174447)
Affinity DataIC50: 367nMAssay Description:Inhibition of TNKS2 (unknown origin) using biotin-NAD+ as substrate incubated for 1 hr in the presence of deoxy-oligonucleotide by ELISA analysis rel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50594027(CHEMBL5174447)
Affinity DataIC50: 551nMAssay Description:Inhibition of TNKS1 (unknown origin) using biotin-NAD+ as substrate incubated for 1 hr in the presence of deoxy-oligonucleotide by ELISA analysis rel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed