BDBM50594351 CHEMBL5178168

SMILES COc1cncc(c1)-c1cccc2nc([C@@H]3CC[C@H](C)N3c3nc(N)nc(N)c3C#N)n(-c3cccc(F)c3)c(=O)c12

InChI Key InChIKey=RLGDGKWUNBYKRD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50594351   

LigandPNGBDBM50594351(CHEMBL5178168)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human PI3Kgamma expressed in baculovirus infected Sf21 insect cells incubated for 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
LigandPNGBDBM50594351(CHEMBL5178168)
Affinity DataIC50: 600nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human PI3Kdelta expressed in baculovirus infected Sf21 insect cells incubated for 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
LigandPNGBDBM50594351(CHEMBL5178168)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human PI3Kalpha expressed in baculovirus infected Sf21 insect cells incubated for 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
LigandPNGBDBM50594351(CHEMBL5178168)
Affinity DataIC50: 4.29E+5nMAssay Description:Inhibition of N-terminal His6-tagged recombinant full length human PI3Kbeta expressed in baculovirus infected Sf21 insect cells incubated for 30 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed