BDBM50594717 CHEMBL5173070

SMILES CN1CCN(CC1)c1ccc(Nc2ncc(Br)c(Nc3ccc4cn[nH]c4c3)n2)cc1

InChI Key InChIKey=AIANAUPKJGDVRP-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50594717   

TargetEpidermal growth factor receptor(Human)
Zhuhai Campus of Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50594717(CHEMBL5173070)
Affinity DataIC50: 43nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human EGFR (669 to 1210 residues) L858R/T790M double mutant expressed in baculovirus infected Sf21 ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Zhuhai Campus of Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50594717(CHEMBL5173070)
Affinity DataIC50: 1.14E+3nMAssay Description:Inhibition of N-terminal GST-tagged recombinant wild type human EGFR (669 to 1210 residues) expressed in baculovirus infected Sf21 cells incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetFibroblast growth factor receptor 1(Human)
Zhuhai Campus of Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50594717(CHEMBL5173070)
Affinity DataIC50: 18nMAssay Description:Inhibition of N-terminal GST-tagged recombinant wild type human FGFR1 (398 to 822 residues) expressed in baculovirus infected Sf21 cells incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Zhuhai Campus of Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50594717(CHEMBL5173070)
Affinity DataIC50: 43nMAssay Description:Inhibition of EGFR L858R/T790M mutant (unknown origin) expressed in baculovirus expression system by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Zhuhai Campus of Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50594717(CHEMBL5173070)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of wild type EGFR (unknown origin) expressed in baculovirus expression system by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Zhuhai Campus of Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50594717(CHEMBL5173070)
Affinity DataIC50: 43nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Zhuhai Campus of Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50594717(CHEMBL5173070)
Affinity DataIC50: 1.14E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetFibroblast growth factor receptor 1(Human)
Zhuhai Campus of Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50594717(CHEMBL5173070)
Affinity DataIC50: 18nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed