BDBM50594846 CHEMBL5209004

SMILES C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(N)=O

InChI Key InChIKey=OAYQFQPLBIBLJE-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50594846   

TargetMu-type opioid receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50594846(CHEMBL5209004)
Affinity DataKi:  0.0900nMAssay Description:Displacement of [3H]DAGO from rat brain MOP incubated for 90 mins by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50594846(CHEMBL5209004)
Affinity DataIC50: 1.70nMAssay Description:Antagonist activity at guinea pig ileum MOPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMu-type opioid receptor(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50594846(CHEMBL5209004)
Affinity DataIC50: 52nMAssay Description:Antagonist activity at mouse vas deferns MOPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetKappa-type opioid receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50594846(CHEMBL5209004)
Affinity DataKi:  617nMAssay Description:Displacement of [3H]U69593 from guinea pig brain KOP incubated for 90 mins by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetDelta-type opioid receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50594846(CHEMBL5209004)
Affinity DataKi:  1.11E+3nMAssay Description:Displacement of [3H][DAla2]deltorphin-I from rat brain DOP incubated for 90 mins by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed