BDBM50594904 CHEMBL5199347

SMILES CN1CCC2(CC1)CCN(CC2)c1ccc(Nc2ncc3cc(C4CC4)n(-c4cccc(n4)C(C)(C)O)c3n2)cc1

InChI Key InChIKey=QENAKPQKNQSLHJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50594904   

TargetWee1-like protein kinase(Human)
Hubei Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50594904(CHEMBL5199347)
Affinity DataIC50: 1nMAssay Description:Displacement of tracer 178 from N-terminal GST-fused human WEE1 (215 to 646 residues) expressed in baculovirus expression system preincubated for 5 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetWee1-like protein kinase(Human)
Hubei Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50594904(CHEMBL5199347)
Affinity DataIC50: 1nMAssay Description:Inhibition of Wee1 (unknown origin) incubated for 60 mins by LanthaScreen Eu-Kinase binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed