BDBM50594945 CHEMBL5180485

SMILES Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COc2ccc(OCCNC(=O)CCc3ccc(c(N)n3)-c3cnc(NCc4c5CCOc5ccc4F)n4cnnc34)cc2)C(C)(C)C)cc1

InChI Key InChIKey=IPOBDFFCDGTMLE-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50594945   

TargetPolycomb protein EED(Human)
Sanquan College of Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50594945(CHEMBL5180485)
Affinity DataKd:  0.631nMAssay Description:Binding affinity to human N-terminal His-6 tagged EED expressed in Escherichia coli strain BL2(DE3) by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPolycomb protein EED(Human)
Sanquan College of Xinxiang Medical University

Curated by ChEMBL
LigandPNGBDBM50594945(CHEMBL5180485)
Affinity DataIC50: 6.80nMAssay Description:Inhibition of human N-terminal His-6 tagged EED expressed in Escherichia coli strain BL2(DE3) by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed