BDBM50595054 CHEMBL5202021

SMILES COc1cc2oc(cc(=O)c2cc1OC)C(=O)Nc1cccc(CN(C)Cc2ccccc2)c1

InChI Key InChIKey=GLPOBZBQMRDBEA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50595054   

TargetAcetylcholinesterase(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50595054(CHEMBL5202021)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetBeta-secretase 1(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50595054(CHEMBL5202021)
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of human BACE-1 using rhodamine-EVNLDAEFK-quencher as peptide substrate incubated for 60 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50595054(CHEMBL5202021)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human LOX-5 using arachidonic acid and ATP as substrate preincubated for 10 mins followed by substrate addition and measured after 20 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed