BDBM50595062 CHEMBL5196827

SMILES O=C(CCN1CCN(Cc2ccccc2)CC1)Nc1ccc2nc3CCCn3c(=O)c2c1

InChI Key InChIKey=ZHIZWWLUDBQEIU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50595062   

TargetBeta-secretase 1(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50595062(CHEMBL5196827)
Affinity DataIC50: 129nMAssay Description:Inhibition of human BACE-1 using Rh-EVNLDAEFK-quencher as peptide substrate incubated for 1 hr in dark by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50595062(CHEMBL5196827)
Affinity DataIC50: 3.29E+3nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate preincubated for 6 mins followed by substrate addition and measured for 12 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAmyloid-beta precursor protein(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50595062(CHEMBL5196827)
Affinity DataIC50: 9.26E+3nMAssay Description:Inhibition of amyloid beta (1 to 42) (unknown origin) self aggregation incubated for 24 hrs by Thioflavin T based fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed