BDBM50595521 CHEMBL5177692

SMILES COc1ccc(-c2nc3cc(ccn3c2NCc2ccccc2)N2CCN(CC2)C2CCCC2)c(OC)c1

InChI Key InChIKey=XHHNBDYVBHBLEW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50595521   

TargetToll-like receptor 9(Human)
Csir-Indian Institute of Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50595521(CHEMBL5177692)
Affinity DataIC50: 526nMAssay Description:Antagonist activity at human TLR9 expressed in HEK-blue hTLR9 cells assessed as inhibition of CpGB-induced NFkappaB activation preincubated with comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Csir-Indian Institute of Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50595521(CHEMBL5177692)
Affinity DataIC50: 4.81E+3nMAssay Description:Antagonist activity at human TLR7 expressed in HEK-blue hTLR7 cells assessed as inhibition of CL264-induced NFkappaB activation preincubated with com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed