BDBM50595664 CHEMBL5207346

SMILES CNCc1c(Cl)cccc1Cn1c2cc[nH]c2c(=O)[nH]c1=S

InChI Key InChIKey=QODCCOQDROIBJO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50595664   

TargetMyeloperoxidase(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50595664(CHEMBL5207346)
Affinity DataIC50: 39nMAssay Description:Inhibition of MPO (unknown origin) measured after 15 mins in presence of H2O2 by chemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetThyroid peroxidase(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50595664(CHEMBL5207346)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of human recombinant TPO (1 to 839 residues) expressed in baculovirus-infected insect cells measured after 15 mins in presence of H2O2 by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMyeloperoxidase(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50595664(CHEMBL5207346)
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of MPO in human HL-60 cells measured after 15 mins in presence of H2O2 by chemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed