BDBM50595666 CHEMBL5200126

SMILES CN[C@H](C)c1cc(Cl)ccc1Cn1c2cc[nH]c2c(=O)[nH]c1=S

InChI Key InChIKey=KMQDMKOHXUMLRM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50595666   

TargetMyeloperoxidase(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50595666(CHEMBL5200126)
Affinity DataIC50: 13nMAssay Description:Inhibition of MPO (unknown origin) measured after 15 mins in presence of H2O2 by chemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetMyeloperoxidase(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50595666(CHEMBL5200126)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of MPO in human HL-60 cells measured after 15 mins in presence of H2O2 by chemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetThyroid peroxidase(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50595666(CHEMBL5200126)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human recombinant TPO (1 to 839 residues) expressed in baculovirus-infected insect cells measured after 15 mins in presence of H2O2 by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed