BDBM50595787 CHEMBL5197526

SMILES NC(=O)c1cn(nc1Nc1cc2COB(O)c2c(Cl)c1)C1COCCC1C#N

InChI Key InChIKey=VRDWLDXWPGUQLN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50595787   

TargetTyrosine-protein kinase JAK1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50595787(CHEMBL5197526)
Affinity DataIC50: 10nMAssay Description:Inhibition of JAK1 (unknown origin) preincubated for 20 mins followed by 33P-ATP addition and measured after 2 hrs by filter binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed