BDBM50596823 CHEMBL5201275

SMILES Cn1cc(CN2CCC(CC2)\C=C\C(=O)NO)c2ccccc12

InChI Key InChIKey=SPYVWCZEYVBQGX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50596823   

TargetPolyamine deacetylase HDAC10(Zebrafish)
Martin-Luther University of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50596823(CHEMBL5201275)
Affinity DataIC50: 58nMAssay Description:Inhibition of zebra fish HDAC10 using Ac-spermidine-AMC as substrate incubated for 25 mins and measured by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Martin-Luther University of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50596823(CHEMBL5201275)
Affinity DataIC50: 2.42E+3nMAssay Description:Inhibition of recombinant human HDAC6 using ZMAL (Z-(Ac)Lys-AMC as substrate incubated for 20 mins and measured by homogenous fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Martin-Luther University of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50596823(CHEMBL5201275)
Affinity DataIC50: 920nMAssay Description:Inhibition of recombinant human HDAC8 using H2N-Arg- His-Lys(Ac)-Lys(Ac)-AMC as substrate incubated for 90 mins and measured after 20 mins by fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed