BDBM50596959 CHEMBL5198990

SMILES Nc1nc(Oc2ccc(NC(=O)NCC(O)=O)cc2)c2cc[nH]c2n1

InChI Key InChIKey=QYMUJFWDEDCLCI-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50596959   

TargetTyrosine-protein kinase JAK2(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50596959(CHEMBL5198990)
Affinity DataKd:  1.97E+4nMAssay Description:Binding affinity to wild type JAK2 JH2 pseudokinase domain (unknown origin) expressed in Sf9 cells and measured upto 30 mins by competitive fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50596959(CHEMBL5198990)
Affinity DataKd:  1.97E+4nMAssay Description:Binding affinity to wild type JAK2 JH2 (unknown origin) assessed as dissociation constant by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed