BDBM50597588 CHEMBL5187631

SMILES Fc1ccc2c(Cc3nnc(Cc4cccc(c4)C#N)n3CCCc3c[nH]cn3)c[nH]c2c1

InChI Key InChIKey=ZYTBRIRSAAUYTD-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50597588   

TargetSomatostatin receptor type 4(Human)
Southern Illinois University Edwardsville

Curated by ChEMBL
LigandPNGBDBM50597588(CHEMBL5187631)
Affinity DataEC50:  7.20nMAssay Description:Agonist activity at recombinant human SST4 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP production measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetSomatostatin receptor type 4(Human)
Southern Illinois University Edwardsville

Curated by ChEMBL
LigandPNGBDBM50597588(CHEMBL5187631)
Affinity DataKi:  6.90nMAssay Description:Displacement of [125I]-Tyr-SRIF 14 from human SST4 receptor expressed in membrane measured after 90 mins by gamma counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetSomatostatin receptor type 2(Human)
Southern Illinois University Edwardsville

Curated by ChEMBL
LigandPNGBDBM50597588(CHEMBL5187631)
Affinity DataKi:  5.88E+3nMAssay Description:Displacement of [125I]-Tyr-SRIF 14 from human SST2A receptor expressed in membrane measured after 90 mins by gamma counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed