BDBM50597850 CHEMBL5184668

SMILES CCOC(=O)Nc1nc2ccc(cc2[nH]1)-c1cc(Cc2n[nH]c(=O)c3ccccc23)ccc1F

InChI Key InChIKey=DCSUGHIXMFUMOQ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50597850   

TargetPoly [ADP-ribose] polymerase 1(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50597850(CHEMBL5184668)
Affinity DataIC50: 5nMAssay Description:Inhibition of PARP1 (unknown origin) incubated for 60 mins by microplate assay kit methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50597850(CHEMBL5184668)
Affinity DataIC50: 50nMAssay Description:Inhibition of PARP2 (unknown origin) incubated for 60 mins by microplate assay kit methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetTriosephosphate isomerase(Human)
Henan University

Curated by ChEMBL
LigandPNGBDBM50597850(CHEMBL5184668)
Affinity DataIC50: 990nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50597850(CHEMBL5184668)
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50597850(CHEMBL5184668)
Affinity DataIC50: 0.0500nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed