BDBM50598320 CHEMBL5174305

SMILES NS(=O)(=O)c1ccc(CCNC(=S)NC(=O)c2ccc3OCOc3c2)cc1

InChI Key InChIKey=HBOIMROWLLXYOH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50598320   

TargetP2X purinoceptor 4(Human)
Comsats University Islamabad

Curated by ChEMBL
LigandPNGBDBM50598320(CHEMBL5174305)
Affinity DataIC50: 1.05E+3nMAssay Description:Antagonist activity against human P2X4R stably transfected in human 1321N1 cells incubated for 30 mins by Fura-2 AM staining based calcium influx ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetP2X purinoceptor 7(Human)
Comsats University Islamabad

Curated by ChEMBL
LigandPNGBDBM50598320(CHEMBL5174305)
Affinity DataIC50: 45nMAssay Description:Antagonist activity against human P2X7R stably transfected in human 1321N1 cells incubated for 30 mins by Fura-2 AM staining based calcium influx ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetP2X purinoceptor 7(Human)
Comsats University Islamabad

Curated by ChEMBL
LigandPNGBDBM50598320(CHEMBL5174305)
Affinity DataIC50: 47nMAssay Description:Antagonist activity against human P2X7R stably transfected in human 1321N1 cells assessed as reduction in BzATP-induced activity incubated for 5 to 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed