BDBM50598622 CHEMBL5181969

SMILES CCOc1ncc2cc(-c3ccc4ncn(C)c4c3)c(=O)n(-c3ccc(OC(F)F)cc3)c2n1

InChI Key InChIKey=DOAANOOOWBAPIM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50598622   

TargetS-adenosylmethionine synthase isoform type-2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50598622(CHEMBL5181969)
Affinity DataIC50: 20nMAssay Description:Inhibition of MAT2A (unknown origin) assessed as S-adenosyl methionine production using L-methionine as substrate pretreated for 60 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed