BDBM50598705 CHEMBL5182374

SMILES [H][C@]12OC[C@@H](Oc3nc(Nc4ccc(N5CCC(CC5)N5CCN(C)CC5)c(Cl)c4)ncc3Cl)[C@@]1([H])OC[C@@H]2O

InChI Key InChIKey=APDFRGIBBFMHRS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50598705   

TargetTyrosine-protein kinase JAK1(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50598705(CHEMBL5182374)
Affinity DataIC50: 672nMAssay Description:Inhibition of GST-tagged recombinant human JAK1 (866 to 1154 residues) expressed in baculovirus infection system by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50598705(CHEMBL5182374)
Affinity DataIC50: 410nMAssay Description:Inhibition of GST tagged recombinant human JAK2 expressed in baculovirus infection system by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50598705(CHEMBL5182374)
Affinity DataIC50: 32nMAssay Description:Inhibition of GST tagged recombinant human JAK3 expressed in baculovirus infection system by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50598705(CHEMBL5182374)
Affinity DataIC50: 170nMAssay Description:Inhibition of human TYK2 by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed