BDBM50598821 CHEMBL5202444

SMILES Cc1c(O)ccc(Cl)c1-n1c(N)c(C(N)=O)c2nc3ccccc3nc12

InChI Key InChIKey=HDTPGKBMQBCWBG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50598821   

LigandPNGBDBM50598821(CHEMBL5202444)
Affinity DataIC50: 10nMAssay Description:Inhibition of N-terminal human recombinant PKMYT1 (76 to 362 residues) expressed in Escherichia coli (DE3) RIL preincubated with compound for 15 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetWee1-like protein kinase(Human)
Repare Therapeutics

Curated by ChEMBL
LigandPNGBDBM50598821(CHEMBL5202444)
Affinity DataIC50: 230nMAssay Description:Inhibition of WEE1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
LigandPNGBDBM50598821(CHEMBL5202444)
Affinity DataIC50: 380nMAssay Description:Inhibition of N-terminal recombinant PKMYT1 (76 to 362 residues) in CCNE1 amplified human FU-OV-1 cells assessed as phosphorylation of CDK1 at Thr14 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed