BDBM50599328 CHEMBL4744973

SMILES CN1CCN(CC1)c1ccc(Nc2ncc3nc(Nc4ccc(F)cc4)n([C@H]4CCN(C4)S(=O)(=O)C4CC4)c3n2)cc1

InChI Key InChIKey=UUFBFTXEDGUXNL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50599328   

TargetEpidermal growth factor receptor(Human)
H. R. Patel Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50599328(CHEMBL4744973)
Affinity DataIC50: 22nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed