BDBM50599334 CHEMBL5200385

SMILES CN1CCN(CC1)c1ccc(Nc2ccc3cc(-c4ccccc4Cl)c(=O)n([C@H]4CC[C@@H](CC4)NC(C)=O)c3c2)cc1C

InChI Key InChIKey=LMRRNKPYCBBKDT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50599334   

TargetEpidermal growth factor receptor(Human)
H. R. Patel Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50599334(CHEMBL5200385)
Affinity DataIC50: 48nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed