BDBM50599454 CHEMBL5183703

SMILES CC[C@H]1N(CC2CCCCC2)c2nc(Nc3ccc(cc3OC)C(=O)NC3CCN(CCCCNC(=O)COc4cccc5C(=O)C(C6CCC(=O)NC6=O)C(=O)c45)CC3)ncc2-n2c(C)nnc12

InChI Key InChIKey=HWCCWYQDFQTRHY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50599454   

TargetSerine/threonine-protein kinase PLK1(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50599454(CHEMBL5183703)
Affinity DataIC50: 310nMAssay Description:Inhibition of recombinant full length human PLK1 using casein as substrate incubated for 40 mins in presence of [gamma-33P]-ATP by radiometric scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50599454(CHEMBL5183703)
Affinity DataIC50: 219nMAssay Description:Inhibition of BRD4 (unknown origin) by alpha-screen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed