BDBM50599471 CHEMBL4277134

SMILES Oc1ccc2nc(NC(=O)Nc3ccc(cc3)C(=O)NCc3ccccc3)sc2c1

InChI Key InChIKey=CMEHUCXLRATIIB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50599471   

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50599471(CHEMBL4277134)
Affinity DataIC50: 63nMAssay Description:Inhibition of human N-terminal His6-tagged DYRK1A expressed in Escherichia coli BL21 (DE3) using KKISGRLSPIMTEQ as substrate incubated in presence of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50599471(CHEMBL4277134)
Affinity DataIC50: 63nMAssay Description:Inhibition of human Dyrk1AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50599471(CHEMBL4277134)
Affinity DataIC50: 130nMAssay Description:Inhibition of Dyrk1B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Human)
German University In Cairo

Curated by ChEMBL
LigandPNGBDBM50599471(CHEMBL4277134)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Dyrk2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed