BDBM50599485 CHEMBL5179449

SMILES FC(F)(F)c1nccc(N[C@H]2CC[C@H](CC2)Nc2ccc3nnc(Br)n3n2)n1

InChI Key InChIKey=UEMGSIWMEYAJDW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50599485   

LigandPNGBDBM50599485(CHEMBL5179449)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human MALT1 assessed as cleavage of substrate using fluorescent labeled Ac-LRSR-Rh110 peptide as substrate incubated for 30 mins follow...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
LigandPNGBDBM50599485(CHEMBL5179449)
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of human MALT1 in human MCF7 cells assessed as MALT1 mediated cleavage of human A20 in cytosol by fluorescence microscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed