BDBM50599538 CHEMBL5206234

SMILES CC1(C)N(C(=S)N(C1=O)c1ccc(C#N)c(c1)C(F)(F)F)c1ccc(cn1)C(=O)Nc1ccccc1N

InChI Key InChIKey=CMWICCMDGCWIRR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50599538   

TargetAndrogen receptor(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50599538(CHEMBL5206234)
Affinity DataIC50: 2.34E+3nMAssay Description:Anti-androgenic activity at androgen receptor (unknown origin) expressed in HEK293 cells by BRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50599538(CHEMBL5206234)
Affinity DataIC50: 6.51E+3nMAssay Description:Inhibition of purified human HDAC1 using Ac-Leu-Gly-(e-Ac)Lys-AMC by fluorometric HDAC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed