BDBM50599542 CHEMBL5173002

SMILES CC1(C)N(C(=S)N(C1=O)c1ccc(C#N)c(c1)C(F)(F)F)c1ccc(nc1)C(=O)Nc1cc(ccc1N)-c1ccccc1

InChI Key InChIKey=JXRMYVJWPGPVDI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50599542   

TargetAndrogen receptor(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50599542(CHEMBL5173002)
Affinity DataIC50: 1.00E+4nMAssay Description:Anti-androgenic activity at androgen receptor (unknown origin) expressed in HEK293 cells by BRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50599542(CHEMBL5173002)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of purified human HDAC1 using Ac-Leu-Gly-(e-Ac)Lys-AMC by fluorometric HDAC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed