BDBM50601002 CHEMBL5208947

SMILES Fc1cc(Cl)ccc1N1CCN(Cc2ccn3c(CC4CC4)nnc3c2C(F)(F)F)CC1

InChI Key InChIKey=KONITDZDOWUETL-UHFFFAOYSA-N

Data  8 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50601002   

TargetMetabotropic glutamate receptor 2(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50601002(CHEMBL5208947)
Affinity DataEC50:  8.30nMAssay Description:Positive allosteric modulation of mGlu2 receptor (unknown origin) expressed in human Flp-In-T-REx-293 cells in presence of L-glutamate by luciferase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50601002(CHEMBL5208947)
Affinity DataEC50:  7.28E+3nMAssay Description:Agonist activity at mGlu2 receptor (unknown origin) expressed in human Flp-In-T-REx-293 cells by luciferase based GloSensor cAMP AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetMetabotropic glutamate receptor 8(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50601002(CHEMBL5208947)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at mGlu8 receptor (unknown origin) expressed in human Flp-In-T-REx-293 cells by luciferase based GloSensor cAMP AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50601002(CHEMBL5208947)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at mGlu5 receptor (unknown origin) expressed in human Flp-In-T-REx-293 cells by luciferase based GloSensor cAMP AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50601002(CHEMBL5208947)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at mGlu1 receptor (unknown origin) expressed in human Flp-In-T-REx-293 cells by luciferase based GloSensor cAMP AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50601002(CHEMBL5208947)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at mGlu6 receptor (unknown origin) expressed in human Flp-In-T-REx-293 cells by luciferase based GloSensor cAMP AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50601002(CHEMBL5208947)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at mGlu4 receptor (unknown origin) expressed in human Flp-In-T-REx-293 cells by luciferase based GloSensor cAMP AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetMetabotropic glutamate receptor 3(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50601002(CHEMBL5208947)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at mGlu3 receptor (unknown origin) expressed in human Flp-In-T-REx-293 cells by luciferase based GloSensor cAMP AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed