BDBM50601034 CHEMBL5191661

SMILES CC(C)C[C@@H](C(=O)N[C@@H](Cc1c[nH]c2c1cccc2)C(=O)OC)NC(=O)[C@H]([C@@H](COc3ccc(cc3)O)N)O

InChI Key InChIKey=WXYVFLSKRTUFAE-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50601034   

TargetEndoplasmic reticulum aminopeptidase 1(Human)
National Centre For Scientific Research "Demokritos

Curated by ChEMBL
LigandPNGBDBM50601034(CHEMBL5191661)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of recombinant ERAP1 (unknown origin) expressed in baculovirus infected Hi-5 insect cells using L-AMC as substrate by flourescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetEndoplasmic reticulum aminopeptidase 2(Human)
National Centre For Scientific Research "Demokritos

Curated by ChEMBL
LigandPNGBDBM50601034(CHEMBL5191661)
Affinity DataIC50: 760nMAssay Description:Inhibition of recombinant ERAP2 (unknown origin) expressed in baculovirus infected Hi-5 insect cells using R-AMC as substrate by flourescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetInterleukin-1 receptor antagonist protein(Human)
National Centre For Scientific Research "Demokritos

Curated by ChEMBL
LigandPNGBDBM50601034(CHEMBL5191661)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of recombinant IRAP (unknown origin) expressed in HEK293S cells using L-AMC as substrate by flourescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetInterleukin-1 receptor antagonist protein(Human)
National Centre For Scientific Research "Demokritos

Curated by ChEMBL
LigandPNGBDBM50601034(CHEMBL5191661)
Affinity DataIC50: 259nMAssay Description:Inhibition of recombinant IRAP (unknown origin) expressed in ovalbumin expressing wild type HEK293S cells assessed as decrease in antigen-mediated IL...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed