BDBM50601452 CHEMBL5185980

SMILES CCc1nc(C)cn1Cc1ccc(Nc2ncc(F)c(Nc3cccc(NC(=O)C=C)c3)n2)cc1

InChI Key InChIKey=HXZIFANRLBZCMF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50601452   

TargetTyrosine-protein kinase BTK(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50601452(CHEMBL5185980)
Affinity DataIC50: 42nMAssay Description:Inhibition of BTK (unknown origin) incubated for 60 mins in the presence of ATP by ADP-Glo reagent based luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50601452(CHEMBL5185980)
Affinity DataIC50: 42nMAssay Description:Inhibition of BTK (unknown origin) incubated for 60 mins by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed