BDBM50601464 CHEMBL5195850

SMILES CCN(CC)c1ccc(\C=C\c2ccccc2C(=O)NC(Cc2ccccc2)C(=O)C(N)=O)cc1

InChI Key InChIKey=LATPLYQWHGFDBR-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50601464   

TargetCathepsin K(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50601464(CHEMBL5195850)
Affinity DataKi:  1.80nMAssay Description:Inhibition of human Cathepsin K assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCathepsin B(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50601464(CHEMBL5195850)
Affinity DataKi:  28nMAssay Description:Inhibition of human Cathepsin B assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCalpain-1 catalytic subunit(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50601464(CHEMBL5195850)
Affinity DataKi:  56nMAssay Description:Inhibition of human Calpain I assessed as dissociation constant using Suc-Leu-Tyr-AMC as substrate preincubated for 15 mins followed by compound addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetProcathepsin L(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50601464(CHEMBL5195850)
Affinity DataKi:  137nMAssay Description:Inhibition of human Cathepsin L assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetCathepsin S(Human)
Niddk

Curated by ChEMBL
LigandPNGBDBM50601464(CHEMBL5195850)
Affinity DataKi:  3.29E+3nMAssay Description:Inhibition of human Cathepsin S assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed