BDBM50601650 CHEMBL5179619

SMILES CC(=O)N[C@@H](Cc1coc2ccccc12)B(O)O

InChI Key InChIKey=XHUQDXLHUWKSRR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50601650   

TargetProteasome subunit beta type-8(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50601650(CHEMBL5179619)
Affinity DataIC50: 18nMAssay Description:Inhibition of human 20S immunoproteasome beta-5i subunit using Suc-LLVY-AMC as substrate preincubated for 2 hrs followed by substrate addition and me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetProteasome subunit beta type-5(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50601650(CHEMBL5179619)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human 20S proteasome beta5 subunit using Suc-LLVY-AMC as substrate preincubated for 2 hrs followed by substrate addition and measured a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetProteasome subunit beta type-5(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50601650(CHEMBL5179619)
Affinity DataIC50: 420nMAssay Description:Inhibition of 20S proteasome beta5 subunit in human A549 cells using Suc-LLVY-luciferin substrate preincubated for 2 hrs followed by substrate additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetProteasome subunit beta type-8(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50601650(CHEMBL5179619)
Affinity DataIC50: 27nMAssay Description:Inhibition of 20S immunoproteasome beta-5i subunit in human PBMC using Ac-ANW-luciferin substrate preincubated for 2 hrs followed by substrate additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed