BDBM50601765 CHEMBL5201102

SMILES COC(=O)c1ccc2c(C(Nc3ccc(cc3)N(C)C(=O)CN3CCN(C)CC3)c3ccccc3)c(O)[nH]c2c1

InChI Key InChIKey=AMHUBFWCCMLLCJ-UHFFFAOYSA-N

Data  15 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50601765   

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
University of Arkansas For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50601765(CHEMBL5201102)
Affinity DataIC50: 2nMAssay Description:Inhibition of RET (unknown origin) by FISH assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
University of Arkansas For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50601765(CHEMBL5201102)
Affinity DataIC50: 99nMAssay Description:Inhibition of VEGFR1 (unknown origin) by FISH assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
University of Arkansas For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50601765(CHEMBL5201102)
Affinity DataIC50: 3nMAssay Description:Inhibition of VEGFR2 (unknown origin) by FISH assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 3(Human)
University of Arkansas For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50601765(CHEMBL5201102)
Affinity DataIC50: 4nMAssay Description:Inhibition of VEGFR3 (unknown origin) by FISH assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
University of Arkansas For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50601765(CHEMBL5201102)
Affinity DataIC50: 18nMAssay Description:Inhibition of PDGFRalpha (unknown origin) by FISH assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
University of Arkansas For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50601765(CHEMBL5201102)
Affinity DataIC50: 28nMAssay Description:Inhibition of PDGFRbeta (unknown origin) by FISH assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetFibroblast growth factor receptor 1(Human)
University of Arkansas For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50601765(CHEMBL5201102)
Affinity DataIC50: 41nMAssay Description:Inhibition of FGFR1 (unknown origin) by FISH assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetFibroblast growth factor receptor 2(Human)
University of Arkansas For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50601765(CHEMBL5201102)
Affinity DataIC50: 47nMAssay Description:Inhibition of FGFR2 (unknown origin) by FISH assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
University of Arkansas For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50601765(CHEMBL5201102)
Affinity DataIC50: 5nMAssay Description:Inhibition of CSF1R (unknown origin) by FISH assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
University of Arkansas For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50601765(CHEMBL5201102)
Affinity DataIC50: 30nMAssay Description:Inhibition of TRKA (unknown origin) by FISH assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetNT-3 growth factor receptor(Human)
University of Arkansas For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50601765(CHEMBL5201102)
Affinity DataIC50: 48nMAssay Description:Inhibition of TRKC (unknown origin) by FISH assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetTyrosine-protein kinase ABL1(Human)
University of Arkansas For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50601765(CHEMBL5201102)
Affinity DataIC50: 12nMAssay Description:Inhibition of ABL1 (unknown origin) by FISH assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
University of Arkansas For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50601765(CHEMBL5201102)
Affinity DataIC50: 6nMAssay Description:Inhibition of KIT (unknown origin) by FISH assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetFibroblast growth factor receptor 4(Human)
University of Arkansas For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50601765(CHEMBL5201102)
Affinity DataIC50: 421nMAssay Description:Inhibition of FGFR4 (unknown origin) by FISH assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetFibroblast growth factor receptor 3(Human)
University of Arkansas For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50601765(CHEMBL5201102)
Affinity DataIC50: 96nMAssay Description:Inhibition of FGFR3 (unknown origin) by FISH assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed