BDBM50601896 CHEMBL5203781

SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H]2CCCN2C(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@@H]2CSSC[C@H](NC(=O)CN)C(=O)N[C@@H](CSSC[C@H](NC1=O)C(N)=O)C(=O)NC(CN)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N2)C(C)C

InChI Key InChIKey=XTMVSVQIYRTKIW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50601896   

TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50601896(CHEMBL5203781)
Affinity DataIC50: 4nMAssay Description:Antagonist activity at human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of ACh-induced current amplitude at -80 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50601896(CHEMBL5203781)
Affinity DataIC50: 21nMAssay Description:Antagonist activity at human alpha3beta2 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of ACh-induced current amplitude at -80 mV ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50601896(CHEMBL5203781)
Affinity DataIC50: 259nMAssay Description:Antagonist activity at human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of ACh-induced current amplitude at -80 mV holdi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50601896(CHEMBL5203781)
Affinity DataIC50: 266nMAssay Description:Antagonist activity at human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of ACh-induced current amplitude at -80 mV holdi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed